Kerbside Consult
Cyberdoc — writing on medicine since 1995

Eliminated, Until It Wasn’t

17/2026  ·  16 September 2026

Two of the world’s largest measles outbreaks in 2026 arrived by entirely different routes — one through disrupted immunisation systems and widening coverage gaps, the other substantially through declining vaccine acceptance. Malaysia, with neither crisis, had 231 outbreaks in 2024 anyway. The clinical disease is identical. The reasons are not.

Measles is one of the most contagious infections known. A single case in an unprotected room leaves virus suspended long enough to infect anyone who enters up to two hours later. Nine out of ten susceptible people exposed to a case will catch it. These numbers have not changed. What has changed, in 2026, is where the susceptible people are — and why they got that way.

This piece is not primarily about the disease. It is about how three very different settings ended up in the same place, and what that means for Malaysia specifically.

Bangladesh and the United States are both in the middle of large measles outbreaks right now. In Bangladesh, the WHO was notified of a significant increase in cases on 4 April 2026, with transmission reported across all eight divisions and 58 of 64 districts. By early April, 9,883 suspected cases and 1,398 laboratory-confirmed cases had been reported, with at least 128 suspected and 21 confirmed deaths. Cases declined in June and July following the emergency vaccination campaign, then resurfaced sharply in August — with daily suspected case counts regularly exceeding 1,200 and daily hospitalisations topping 1,000. As of 16 September 2026, 172,720 suspected cases, 19,933 laboratory-confirmed infections, and 1,030 deaths classified by DGHS as confirmed or suspected measles deaths — comprising 100 confirmed and 930 suspected measles deaths — had been recorded since 15 March, with more than 152,000 patients hospitalised. The outbreak remains active; authorities are preparing a further round of vaccinations focused on reaching children missed by previous campaigns. In the United States, 3,134 confirmed cases had been reported across 47 jurisdictions as of 3 September 2026 — the highest annual total in more than 35 years — with two measles-associated deaths in Pennsylvania under CDC review.

Neither outbreak is an isolated event. In January 2026, WHO confirmed that six countries — Armenia, Austria, Azerbaijan, Spain, the United Kingdom, and Uzbekistan — had lost their measles elimination status, joining Canada, which lost it the previous year. Mexico, India, Yemen, Pakistan, and most of continental Europe are all in active outbreak. In England alone, 933 cases were reported in the first part of 2026. Across the Americas, PAHO documented a 32-fold surge in cases in 2025 compared to the prior period. Globally, first-dose measles vaccine coverage stood at 84% in 2025. In 2024, an estimated 95,000 people died from measles — mostly children under five — despite the availability of a safe and effective vaccine that has averted 59 million deaths since 2000. The 2026 figures, when they are complete, will be worse.

Bangladesh and the United States are the two largest and most structurally distinct outbreaks within this wider picture. The clinical disease in Dhaka and in South Carolina is the same. The reasons are not.

Countries with verified measles elimination status, 2018–2023
Source: WHO/CDC annual elimination assessments, as reported in MMWR annual series  ·  Figures are verified totals from regional verification commissions  ·  2024–2026: see note below
Verified elimination (MMWR)
2018Endemic transmission was re-established in Albania, Czechia, Greece and the United Kingdom. Global total: 82.
2019Endemic transmission was re-established in Brazil. Global total rises to 83 as other countries achieve or regain verification.
2021Sharp fall to 76: multiple countries lose status. The rebound to 83 in 2022 illustrates that totals reflect verification cycles — countries lose, regain, and newly achieve elimination status.
After 2023Canada subsequently lost elimination status (2025). In 2026, Armenia, Austria, Azerbaijan, Spain, the United Kingdom and Uzbekistan were reported to have lost elimination status. Because WHO verification is conducted through regional commissions on their own cycles — and countries may also regain status or newly achieve it — these subsequent losses cannot simply be subtracted from the 2023 global total to produce a reliable estimated 2026 figure.
Measles in four numbers
~90%of susceptible close contacts infected by a single case
4 daysinfectious before the rash appears
93%protection after one MMR dose
97%protection after two doses

What the disease is

Measles spreads through respiratory droplets and airborne particles. It infects only humans and has no animal reservoir — which is why measles is theoretically eradicable, and why sustained transmission is ultimately preventable when sufficiently high population immunity is maintained. The incubation period runs from 10 to 14 days from exposure to the onset of symptoms. A person can transmit measles from about four days before until four days after the rash appears — making presymptomatic recognition and isolation difficult.

The illness runs in two stages. The prodrome lasts three to five days: high fever, runny nose, cough, and conjunctivitis — the “three Cs” — followed by Koplik’s spots, a highly characteristic early finding. Koplik’s spots are small, bluish-white specks on a red base on the inside of the cheek, typically opposite the lower molars. They appear one to two days before the rash and disappear within 48 hours of its onset. In the appropriate clinical and epidemiological setting, they should immediately raise measles to the top of the differential diagnosis and prompt notification and laboratory confirmation. Most clinicians who have not encountered measles in practice miss them. Photograph them immediately — they are gone within 48 hours. What to Do If You Think It’s Measles covers the immediate clinical steps.

Suspected measles should not sit in a waiting room: isolate the patient promptly, use appropriate airborne precautions, and notify public health authorities without waiting for laboratory confirmation.

The exanthem begins on day three to five: a maculopapular rash starting at the hairline and behind the ears, spreading downward over two to three days. It blanches under pressure, which distinguishes it from petechial and purpuric rashes. Recovery takes another week.

Complications are common enough that the word “uncomplicated” deserves scrutiny every time it is used. Diarrhoea occurs in roughly 8% of cases and is the leading cause of death in young children in low-income settings. Pneumonia — viral or secondary bacterial — occurs in about 5% and is the leading cause of measles mortality overall. Otitis media in about 7%, with a significant risk of permanent hearing loss. Acute disseminated encephalomyelitis occurs in about 1 in 1,000 cases, with 10 to 20% mortality and frequent permanent deficits in survivors. Subacute sclerosing panencephalitis — SSPE — is uniformly fatal, presenting years to a decade after the original infection, and occurs in roughly 1 in 10,000 cases — with much higher rates in children infected before their second birthday. Malnutrition, vitamin A deficiency, and immunocompromise each substantially worsen outcomes.

This matters particularly in Bangladesh. High levels of malnutrition among children were identified by UNICEF as a critical risk factor amplifying the severity and death rate of the current outbreak — one in four Bangladeshi children under five are stunted, and one in ten suffer from acute malnutrition — against the background of a reported case-fatality rate of approximately 1%, compared with around 0.1–0.3% in the United States. Malnutrition is likely one contributor to severity, but differences in surveillance, ascertainment, age distribution and access to care all play a role in that comparison. Measles in pregnancy is associated with premature labour, miscarriage, and low birthweight.

What treatment consists of

There is no antiviral drug specific to measles. Supportive care includes adequate hydration, antipyretics, and close monitoring for complications. Antibiotics are indicated when secondary bacterial infection is suspected or confirmed, particularly bacterial pneumonia or otitis media.

Vitamin A is actively prescribed, not merely supportive. WHO recommends two doses on consecutive days for all children under five with measles — 200,000 IU for children over 12 months, 100,000 IU for infants 6 to 11 months, 50,000 IU for infants under 6 months — with a third dose 4 to 6 weeks later if there are clinical signs of vitamin A deficiency such as Bitot’s spots. Vitamin A supplementation has been associated with reduced morbidity and mortality in children with measles, particularly in young children and populations at risk of vitamin A deficiency; the evidence is strongest in settings where deficiency is prevalent. In Bangladesh, only one of the two annual supplementation rounds was completed in 2025 — a fact worth holding when reviewing the outbreak’s death toll.

For SSPE there is no curative treatment; for severe or immunocompromised measles, ribavirin has been used off-label with limited evidence. With measles, prevention does what treatment cannot.

The vaccine in detail

The measles vaccine is a live attenuated virus, given as part of the combined MMR (measles-mumps-rubella) or MMRV formulation. One dose is approximately 93% effective; two doses are 97% effective. The second dose is primarily intended to immunise those who failed to respond to the first dose, rather than simply to boost waning immunity. Measles and rubella protection from the two-dose schedule is durable across decades of follow-up data.

Most countries give the first dose at 12 to 15 months and the second at 4 to 6 years. Malaysia’s schedule is compressed: first dose at nine months, second at 12 months, driven by continuing regional circulation. The nine-month dose in a child with residual maternal antibodies may have lower immunogenicity than one given after 12 months — this is the trade-off the schedule accepts in exchange for earlier coverage.

Three situations modify the standard schedule. In outbreak settings, WHO allows vaccination from six months; Bangladesh lowered the eligibility age to six months during the current outbreak, with doses given before 12 months not counting toward the standard series and requiring re-dosing later. For infants aged 6 to 11 months travelling to areas with active measles transmission — which in 2026 includes many countries and regions worldwide — one MMR dose is recommended before departure, with two further doses required at routine ages on return. For post-exposure prophylaxis, MMR given within 72 hours of exposure may prevent or modify infection; immunoglobulin given within six days is the alternative for those who cannot receive live vaccine — immunocompromised individuals, infants under six months, pregnant women.

Because measles is so contagious, sustained elimination generally requires at least 95% population coverage with two doses — and that coverage must be distributed evenly rather than concentrated in national averages. In the United States, only 10 states reached 95% among kindergartners in the 2025–2026 school year, against a national average that has fallen from 95.2% in 2019 to 92.4% — and Idaho’s coverage stands at 78.5%. That gap is measurable. What is happening in the United States is the epidemiological consequence of susceptible populations accumulating within communities.

Bangladesh: when a programme frays

Bangladesh entered 2026 with widening immunisation gaps, depleted vaccine stocks, and a growing population of zero-dose children. A nationwide MR vaccine stockout between 2024 and 2025 — combined with the absence of any nationwide supplementary measles-rubella campaign since 2020 — had left large cohorts of unprotected children by the time the outbreak began.

After Sheikh Hasina’s government was ousted in 2024, the interim government introduced procurement reforms shifting away from UNICEF’s system toward open bidding. Rana Flowers, UNICEF’s Representative to Bangladesh, said she warned the interim government on at least ten separate occasions. As she put it at a press conference: “I sat with the interim adviser and the staff on at least 10 occasions, saying, we are worried. Look at my face. I am worried.” The political transition and procurement disruption appear to have compounded pre-existing immunity gaps and declining routine coverage — the kind of accumulated vulnerabilities that WHO and UNICEF describe as typically underlying measles resurgences rather than any single cause. The virus found the resulting gap.

The demographic picture, documented in UNICEF’s Situation Report #1, is stark: 81% of cases in children under five, 34% in infants under nine months who were below vaccination age, 72% in unvaccinated individuals, 16% in the partially vaccinated. At the Infectious Diseases Hospital in Dhaka, over 90 patients were admitted in a single day. The Government allocated Tk 604 crore (US$49.3 million) for emergency vaccine procurement and launched a phased emergency measles-rubella vaccination campaign beginning 5 April in 30 high-risk upazilas, progressively expanding it nationwide over the following weeks. By 28 May, 18 million had been vaccinated. Cases declined in June and July — then resurfaced sharply in August, with daily suspected cases regularly exceeding 1,200 and daily hospitalisations topping 1,000. The DGHS director general attributed the resurgence to children who had not received the vaccine; an additional intensive vaccination programme and a further campaign planned for later in September are underway. As of 16 September 2026, 172,720 suspected cases, 19,933 laboratory-confirmed infections, and 1,030 deaths — comprising 100 confirmed and 930 suspected measles deaths — had been recorded since 15 March, with more than 152,000 patients hospitalised. The DGHS spokesman acknowledged that herd immunity had not been achieved, and authorities are preparing a further targeted round of vaccinations focused on micro-planning — identifying and reaching susceptible children community by community — rather than another broad national campaign. The pattern illustrates a point the numbers alone do not: vaccination campaigns, however large, take time to interrupt established transmission chains, and infants below nine months — too young for routine vaccination — remain particularly vulnerable while community transmission continues.

The United States: when a choice becomes a policy

The United States declared measles eliminated in 2000. As of 10 September 2026, 3,294 confirmed cases had been reported across 47 jurisdictions — the highest annual total since the US declared measles eliminated in 2000 — with 95% in unvaccinated individuals or those with unknown vaccination status. 38 outbreaks have been recorded in 2026, with 95% of confirmed cases outbreak-associated. Pennsylvania has recorded two measles-associated deaths: the Lancaster County coroner confirmed a measles-associated infant death, and a 40-year-old unvaccinated woman died from measles-related complications on 13 September 2026 — a rare adult fatality, and the second confirmed death of the outbreak. CDC's National Center for Health Statistics had not yet formally recorded either death in its national count at the time of publication, noting it is developing standardised classification criteria in coordination with state epidemiologists.

Dr Jennifer Nuzzo, who heads the Pandemic Center at Brown University, said in a July 2026 NPR interview that the US should by all measures already have lost its eliminated status, describing the pattern as “Whac-A-Mole” — states that contained outbreaks are seeing recurrence, pointing to re-establishing endemic transmission rather than isolated events. She attributed the resurgence to vaccine hesitancy driven by political rhetoric and noted that confusing messaging from the Department of Health and Human Services had complicated the public health response.

The mechanism here appears different from Bangladesh. Bangladesh’s coverage fell because a public health system frayed under political transition and procurement disruption. In the United States, by contrast, vaccine hesitancy and refusal have become important drivers of declining coverage in some communities, alongside other local barriers to vaccination. Several outbreaks have been concentrated in some Mennonite and Amish communities where vaccination coverage has been substantially below the level needed to prevent sustained transmission, even where overall state coverage appears adequate. D8 genotype transmission has been documented across the United States, Canada and Mexico, illustrating how measles can move rapidly across borders through susceptible populations. A 35-year high in a wealthy country with established vaccine supply, extensive cold-chain infrastructure and broadly available vaccination cannot be explained primarily by vaccine scarcity. It is, to a substantial degree, a decision aggregate.

A brief note on Malaysia

Malaysia is not in a measles crisis, but it is not a disinterested observer. MOH launched a nationwide supplementary immunisation activity in August 2025, targeting children aged 6 to 59 months for a third dose, with stated national MMR coverage exceeding 95% annually. That headline figure is reassuring. The detail behind it is less so.

In a written parliamentary reply dated 27 August 2025, as reproduced in full by Ova/Galen Centre and reported by CodeBlue, Health Minister Dzulkefly Ahmad confirmed that Malaysia recorded 3,791 measles cases in 2024 — nearly double the 2,002 cases in 2023, and a 693% increase from 2020. Sabah accounted for 2,015 of those 3,791 cases, more than half the national total. The number of outbreaks rose from 112 in 2023 to 231 in 2024. And despite national coverage exceeding 95%, only 62% of districts had actually reached that threshold. Administrative national coverage, however, is not the same thing as evenly distributed population immunity: district-level gaps, missed second doses and primary vaccine failure leave susceptible clusters behind. Malaysia's National Fatwa Council has declared the MMR vaccine permissible under Islamic law, and MOH provides it free of charge for citizens. Non-citizen residents, however, face a registration fee and a per-dose charge that places routine immunisation out of reach for low-income undocumented families. Persistent hesitancy also exists in some communities, driven partly by online misinformation about vaccine ingredients — concerns that official religious guidance has not fully resolved at the level of individual parents making individual decisions. A 2023 analysis in BMC Public Health found that no Malaysian birth cohort has achieved 95% effective population immunity since the programme began in 1982, and attributes the persistence of measles in Malaysia specifically to pockets of insufficient coverage. The WHO Western Pacific region — which includes Malaysia — saw measles cases increase 743% between 2022 and 2024, and as of early 2025 Malaysia was specifically named as a country with continued active transmission.

The lesson from both outbreaks is the same. Coverage numbers are averages, and measles does not respect averages. It finds the unprotected fraction.

Bangladesh and the United States arrived at the same epidemiological destination by different routes: one through disruption and gaps in delivery, the other substantially through declining vaccine acceptance. Malaysia offers a third warning — that national averages can conceal local vulnerability. Measles is indifferent to the reason immunity was lost. It needs only enough susceptible people to find one another.

What the Malaysia figures mean for Malaysians travelling abroad — and for families planning to travel with young children or infants — is covered in the companion piece Before You Travel: Measles and the MMR.

Disclaimer The views expressed are my own and do not represent those of any employer, client, institution or organisation with which I am or have been associated. Nothing here is medical, legal or financial advice. Case and outcome figures for the Bangladesh outbreak are from a fast-moving situation and may have changed between writing and publication; readers should verify current figures against the WHO disease outbreak news page and the Bangladesh DGHS bulletins directly. The death toll cited reflects figures available as of 16 September 2026; the outbreak is ongoing.
Acknowledgment The author thanks Prof Lam Sai Kit, Emeritus Professor of the University of Malaya and former Head of the Department of Medical Microbiology, University of Malaya, and past President of the Asia Pacific Society for Medical Virology, for his review of this piece and his suggested additions on vaccine hesitancy and access barriers in the Malaysian context.

Sources worth your time

WHO Measles Fact Sheet
WHO, updated 15 July 2026.
The primary global reference — updated figures for 2024 and 2025, including 95,000 deaths in 2024, 84% first-dose coverage in 2025, and 59 million deaths averted since 2000. The authoritative source for vitamin A dosing guidance and the two-dose schedule rationale.
Bangladesh Measles Outbreak 2026: Situation Report #1
UNICEF Bangladesh, 8 April 2026.
Primary operational document for the early outbreak. The source for the 81%/34%/72%/16% demographic breakdown, the vaccine stockout, hospital system strain, and the emergency campaign scope. Read this before citing any single figure from the Bangladesh section.
WHO Disease Outbreak News — Measles in Bangladesh
WHO, 23 April 2026.
The authoritative WHO risk assessment, with figures to 14 April, geographic breakdown by division, the confirmed cross-border risk assessment for India and Myanmar, and the formal public health advice including post-exposure prophylaxis recommendations.
Measles transmission and urgent interventions for child death prevention in Bangladesh
Discover Social Science and Health, June 2026.
The most current peer-reviewed source for Bangladesh figures through 8 June 2026: 80,104 suspected, 9,779 confirmed, 628 deaths. Also provides the Bangladesh CFR comparison (approximately 1%) against the US (0.1–0.3%) and the malnutrition context.
More than 500 people have died in Bangladesh measles outbreak
NPR, 28 May 2026.
The report that drew international attention to the outbreak. Contains the on-the-record statement from Rana Flowers, UNICEF Representative to Bangladesh, that she warned the interim government on at least ten separate occasions. The primary source for that attribution.
More than 2,000 measles cases reported in the U.S., outpacing 2025’s total
NPR, 27 July 2026.
Interview with Dr Jennifer Nuzzo, Pandemic Center at Brown University. The source for her assessment that the US should already have lost its eliminated status, the Whac-A-Mole description, and the HHS messaging attribution.
Malaysia measles cases increased 693% from 2020 to 2024
Ova / Galen Centre, 18 September 2025.
Reproduces Health Minister Dzulkefly Ahmad’s written parliamentary reply of 27 August 2025 in full. Primary source for the 3,791 cases, 231 outbreaks, Sabah accounting for 2,015 cases, and only 62% of districts reaching 95% MMR coverage in 2024.
Evaluating Effective Measles Vaccine Coverage in the Malaysian Population
BMC Public Health, 2023.
Peer-reviewed analysis concluding that no Malaysian birth cohort has achieved 95% effective population immunity since 1982. The source for the argument that stated national coverage overstates effective protection.
Progress Toward Measles Elimination — Worldwide, 2000–2023
MMWR, November 2024.
Primary annual surveillance report from WHO and CDC. The source for elimination status counts and MCV1 coverage trend. The baseline against which 2025–2026 losses are measured.
Measles: Plan for Travel — CDC
US Centers for Disease Control and Prevention, 2026.
The primary travel-specific advisory. The source for the 90% exposure-to-infection risk for unvaccinated travellers, pre-departure vaccination timing, and post-exposure prophylaxis options. The clearest single document to hand to a patient or family planning international travel.

Full references

Every claim in this article is linked inline. This list covers all sources cited, in order of first appearance.

1. UNICEF Bangladesh Situation Report #1 — Measles Outbreak, 8 April 2026

2. Measles transmission and urgent interventions for child death prevention in Bangladesh — Discover Social Science and Health, June 2026

3. WHO Disease Outbreak News — Measles in Bangladesh, 23 April 2026

4. Measles resurges in August — The Daily Star Bangladesh, August 2026

4a. Bangladesh measles outbreak update — Reuters, 9 September 2026

4b. Measles death toll reaches 1,030, eight more die in 24 hours — Dhaka Tribune, 16 September 2026

4c. Why Bangladesh is struggling against measles despite 20 million vaccines — Al Jazeera, 16 September 2026

5. NPR — More than 500 people have died in Bangladesh measles outbreak, 28 May 2026

6. Measles resurgence in Bangladesh, 2026: A warning of fragile immunization gains — IJID editorial, published online 6 May 2026; volume 170, September 2026

7. NPR — More than 2,000 measles cases reported in the U.S., outpacing 2025’s total, 27 July 2026

7a. 40-year-old woman dies from measles in Pennsylvania — CNN, 13 September 2026

8. US Measles Cases and Outbreaks — CDC (updated weekly)

9. Measles disease outbreaks are surging again globally in 2026 — Virulence / PMC, August 2026

10. Measles Multi-Country Outbreak 2026 — PAHO

11. Many Countries Eliminated Measles. Why Is It Coming Back? — Council on Foreign Relations, April 2026

12. WHO Measles Fact Sheet — updated 15 July 2026

13. WHO Position Paper on Measles Vaccines, April 2017

14. Progress towards measles elimination — worldwide, 2000–2024. Weekly Epidemiological Record No 48, 2025

15. Progress Toward Measles Elimination — Worldwide, 2000–2023 — MMWR, November 2024

16. Measles Vaccine Recommendations — CDC

17. WHO Global Health Observatory — Measles, number of reported cases

18. Reported cases of measles — Our World in Data (sourced from WHO GHO)

19. Malaysia measles cases increased 693% from 2020 to 2024 — Ova / Galen Centre, September 2025

20. MOH Launches Nationwide Measles Immunisation Campaign for Third Jab — CodeBlue, August 2025

21. Evaluating Effective Measles Vaccine Coverage in the Malaysian Population — BMC Public Health, 2023

22. Community-Based Intervention to Improve Measles Vaccination Completion in Sabah — BMC Infectious Diseases, 2025

23. Continued increase in measles cases in the Western Pacific Region — WHO WPRO, March 2025

24. The Return of Measles: A Cautionary Tale — CodeBlue, December 2025

25. Before You Travel: Measles and the MMR — Kerbside Consult

26. What to Do If You Think It’s Measles — Kerbside Consult

Published 17/2026  ·  16 September 2026  ·  Kerbside Consult  ·  vadscorner.com